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Protein kinase C‐dependent regulation of ClC‐1 channels in active human muscle and its effect on fast and slow gating

KEY POINTS: Regulation of ion channel function during repeated firing of action potentials is commonly observed in excitable cells. Recently it was shown that muscle activity is associated with rapid, protein kinase C (PKC)‐dependent ClC‐1 Cl(−) channel inhibition in rodent muscle. While this PKC‐de...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Riisager, Anders, de Paoli, Frank Vincenzo, Yu, Wei‐Ping, Pedersen, Thomas Holm, Chen, Tsung‐Yu, Nielsen, Ole Bækgaard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908021/
https://ncbi.nlm.nih.gov/pubmed/26857341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271556
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