p62, upregulated during preneoplasia, induces hepatocellular carcinogenesis by maintaining survival of stressed HCC-initiating cells

p62 is a ubiquitin-binding autophagy receptor and signaling protein that accumulates in premalignant liver diseases and most hepatocellular carcinomas (HCC). Although p62 was proposed to participate in formation of benign adenomas in autophagy-deficient livers, its role in HCC initiation was not exp...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer Cell
Autors principals: Umemura, Atsushi, He, Feng, Taniguchi, Koji, Nakagawa, Hayato, Yamachika, Shinichiro, Font-Burgada, Joan, Zhong, Zhenyu, Subramaniam, Shankar, Raghunandan, Sindhu, Duran, Angeles, Linares, Juan F, Reina-Campos, Miguel, Umemura, Shiori, Valasek, Mark A., Seki, Ekihiro, Yamaguchi, Kanji, Koike, Kazuhiko, Itoh, Yoshito, Diaz-Meco, Maria T., Moscat, Jorge, Karin, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907799/
https://ncbi.nlm.nih.gov/pubmed/27211490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.04.006
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars