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Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation
The essential process of protein secretion is achieved by the ubiquitous Sec machinery. In prokaryotes, the drive for translocation comes from ATP hydrolysis by the cytosolic motor-protein SecA, in concert with the proton motive force (PMF). However, the mechanism through which ATP hydrolysis by Sec...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4907695/ https://ncbi.nlm.nih.gov/pubmed/27183269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15598 |
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