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Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation
The essential process of protein secretion is achieved by the ubiquitous Sec machinery. In prokaryotes, the drive for translocation comes from ATP hydrolysis by the cytosolic motor-protein SecA, in concert with the proton motive force (PMF). However, the mechanism through which ATP hydrolysis by Sec...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4907695/ https://ncbi.nlm.nih.gov/pubmed/27183269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15598 |
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