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Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation
The essential process of protein secretion is achieved by the ubiquitous Sec machinery. In prokaryotes, the drive for translocation comes from ATP hydrolysis by the cytosolic motor-protein SecA, in concert with the proton motive force (PMF). However, the mechanism through which ATP hydrolysis by Sec...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4907695/ https://ncbi.nlm.nih.gov/pubmed/27183269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15598 |
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