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Optical electrophysiology for probing function and pharmacology of voltage-gated ion channels
Voltage-gated ion channels mediate electrical dynamics in excitable tissues and are an important class of drug targets. Channels can gate in sub-millisecond timescales, show complex manifolds of conformational states, and often show state-dependent pharmacology. Mechanistic studies of ion channels t...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4907688/ https://ncbi.nlm.nih.gov/pubmed/27215841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15202 |
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