IGF-1 receptor targeted nanoparticles for image-guided therapy of stroma-rich and drug resistant human cancer

Low drug delivery efficiency and drug resistance from highly heterogeneous cancer cells and tumor microenvironment represent major challenges in clinical oncology. Growth factor receptor, IGF-1R, is overexpressed in both human tumor cells and tumor associated stromal cells. The level of IGF-1R expre...

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Bibliografiske detaljer
Udgivet i:Proc SPIE Int Soc Opt Eng
Main Authors: Zhou, Hongyu, Qian, Weiping, Uckun, Fatih M., Zhou, Zhiyang, Wang, Liya, Wang, Andrew, Mao, Hui, Yang, Lily
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907525/
https://ncbi.nlm.nih.gov/pubmed/27313332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/12.2224914
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