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IGF-1 receptor targeted nanoparticles for image-guided therapy of stroma-rich and drug resistant human cancer

Low drug delivery efficiency and drug resistance from highly heterogeneous cancer cells and tumor microenvironment represent major challenges in clinical oncology. Growth factor receptor, IGF-1R, is overexpressed in both human tumor cells and tumor associated stromal cells. The level of IGF-1R expre...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc SPIE Int Soc Opt Eng
Auteurs principaux: Zhou, Hongyu, Qian, Weiping, Uckun, Fatih M., Zhou, Zhiyang, Wang, Liya, Wang, Andrew, Mao, Hui, Yang, Lily
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907525/
https://ncbi.nlm.nih.gov/pubmed/27313332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/12.2224914
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