Responder Interferon λ Genotypes Are Associated With Higher Risk of Liver Fibrosis in HIV–Hepatitis C Virus Coinfection

Background. Liver fibrosis progresses faster in individuals coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV). Interferon λ3 (IFN-λ3) has both antiviral and proinflammatory properties. Genotypes at IFNL single-nucleotide proteins (SNPs; rs12979860CC and rs8099917TT) are...

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Dettagli Bibliografici
Pubblicato in:J Infect Dis
Autori principali: Moqueet, Nasheed, Cooper, Curtis, Gill, John, Hull, Mark, Platt, Robert W., Klein, Marina B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907413/
https://ncbi.nlm.nih.gov/pubmed/26984148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw088
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