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Identification of differentially methylated loci using wavelet-based functional mixed models

Motivation: DNA methylation is a key epigenetic modification that can modulate gene expression. Over the past decade, a lot of studies have focused on profiling DNA methylation and investigating its alterations in complex diseases such as cancer. While early studies were mostly restricted to CpG isl...

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Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Lee, Wonyul, Morris, Jeffrey S.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907398/
https://ncbi.nlm.nih.gov/pubmed/26559505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv659
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