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Evaluation on antithrombotic effect of aspirin eugenol ester from the view of platelet aggregation, hemorheology, TXB(2)/6-keto-PGF(1α) and blood biochemistry in rat model

BACKGROUND: Based on the prodrug principle, aspirin and eugenol, as starting precursors, were esterified to synthesize aspirin eugenol ester (AEE). The aim of the present study was to evaluate the antithrombotic effect of AEE in an animal disease model. In order to compare the therapeutic effects of...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Ma, Ning, Liu, Xi-Wang, Yang, Ya-Jun, Shen, Dong-Shuai, Zhao, Xiao-Le, Mohamed, Isam, Kong, Xiao-Jun, Li, Jian-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907079/
https://ncbi.nlm.nih.gov/pubmed/27296110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-016-0738-0
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