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Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity

BACKGROUND: Phosphodiesterase 6 (PDE6) is a protein complex that hydrolyses cGMP and acts as the effector of the vertebrate phototransduction cascade. The PDE6 holoenzyme consists of catalytic and inhibitory subunits belonging to two unrelated gene families. Rods and cones express distinct genes fro...

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Veröffentlicht in:BMC Evol Biol
Hauptverfasser: Lagman, David, Franzén, Ilkin E., Eggert, Joel, Larhammar, Dan, Abalo, Xesús M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906994/
https://ncbi.nlm.nih.gov/pubmed/27296292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-016-0695-z
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