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Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity

BACKGROUND: Phosphodiesterase 6 (PDE6) is a protein complex that hydrolyses cGMP and acts as the effector of the vertebrate phototransduction cascade. The PDE6 holoenzyme consists of catalytic and inhibitory subunits belonging to two unrelated gene families. Rods and cones express distinct genes fro...

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Detalhes bibliográficos
Publicado no:BMC Evol Biol
Main Authors: Lagman, David, Franzén, Ilkin E., Eggert, Joel, Larhammar, Dan, Abalo, Xesús M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906994/
https://ncbi.nlm.nih.gov/pubmed/27296292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-016-0695-z
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