An autoradiographic evaluation of AV-1451 Tau PET in dementia

BACKGROUND: It is essential to determine the specificity of AV-1451 PET for tau in brain imaging by using pathological comparisons. We performed autoradiography in autopsy-confirmed Alzheimer disease and other neurodegenerative disorders to evaluate the specificity of AV-1451 binding for tau aggrega...

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Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Lowe, Val J., Curran, Geoffry, Fang, Ping, Liesinger, Amanda M., Josephs, Keith A., Parisi, Joseph E., Kantarci, Kejal, Boeve, Bradley F., Pandey, Mukesh K., Bruinsma, Tyler, Knopman, David S., Jones, David T., Petrucelli, Leonard, Cook, Casey N., Graff-Radford, Neill R., Dickson, Dennis W., Petersen, Ronald C., Jack, Clifford R., Murray, Melissa E.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906968/
https://ncbi.nlm.nih.gov/pubmed/27296779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0315-6
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