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Over-Expressed Pathogenic miRNAs in Alzheimer’s Disease (AD) and Prion Disease (PrD) Drive Deficits in TREM2-Mediated Aβ42 Peptide Clearance

One prominent and distinguishing feature of progressive, age-related neurological diseases such as Alzheimer’s disease (AD) and prion disease (PrD) is the gradual accumulation of amyloids into dense, insoluble end-stage protein aggregates. These polymorphic proteolipid lesions are known to contribut...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Aging Neurosci
Main Authors: Zhao, Yuhai, Jaber, Vivian, Lukiw, Walter J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906923/
https://ncbi.nlm.nih.gov/pubmed/27378912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00140
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