Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine

BACKGROUND: The incidence of hepatocellular carcinoma with nonalcoholic steatohepatitis is increasing, and its clinicopathological features are well established. Several animal models of nonalcoholic steatohepatitis have been developed to facilitate its study; however, few fully recapitulate all its...

Full description

Saved in:
Bibliographic Details
Published in:BMC Gastroenterol
Main Authors: Kishida, Norihiro, Matsuda, Sachiko, Itano, Osamu, Shinoda, Masahiro, Kitago, Minoru, Yagi, Hiroshi, Abe, Yuta, Hibi, Taizo, Masugi, Yohei, Aiura, Koichi, Sakamoto, Michiie, Kitagawa, Yuko
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906823/
https://ncbi.nlm.nih.gov/pubmed/27296438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-016-0477-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items