Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine

BACKGROUND: The incidence of hepatocellular carcinoma with nonalcoholic steatohepatitis is increasing, and its clinicopathological features are well established. Several animal models of nonalcoholic steatohepatitis have been developed to facilitate its study; however, few fully recapitulate all its...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Kishida, Norihiro, Matsuda, Sachiko, Itano, Osamu, Shinoda, Masahiro, Kitago, Minoru, Yagi, Hiroshi, Abe, Yuta, Hibi, Taizo, Masugi, Yohei, Aiura, Koichi, Sakamoto, Michiie, Kitagawa, Yuko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906823/
https://ncbi.nlm.nih.gov/pubmed/27296438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-016-0477-5
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