Učitavanje...
Internal guide RNA interactions interfere with Cas9-mediated cleavage
The CRISPR/Cas system uses guide RNAs (gRNAs) to direct sequence-specific DNA cleavage. Not every gRNA elicits cleavage and the mechanisms that govern gRNA activity have not been resolved. Low activity could result from either failure to form a functional Cas9–gRNA complex or inability to recognize...
Spremljeno u:
| Izdano u: | Nat Commun |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906408/ https://ncbi.nlm.nih.gov/pubmed/27282953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11750 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|