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Urinary miR-16 transactivated by C/EBPβ reduces kidney function after ischemia/reperfusion–induced injury

Ischemia-reperfusion (I/R) induced acute kidney injury (AKI) is regulated by transcriptional factors and microRNAs (miRs). However, modulation of miRs by transcriptional factors has not been characterized in AKI. Here, we found that urinary miR-16 was 100-fold higher in AKI patients. MiR-16 was dete...

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Foilsithe in:Sci Rep
Main Authors: Chen, Hsi-Hsien, Lan, Yi-Fan, Li, Hsiao-Fen, Cheng, Ching-Feng, Lai, Pei-Fang, Li, Wei-Hua, Lin, Heng
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906401/
https://ncbi.nlm.nih.gov/pubmed/27297958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27945
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