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Urinary miR-16 transactivated by C/EBPβ reduces kidney function after ischemia/reperfusion–induced injury

Ischemia-reperfusion (I/R) induced acute kidney injury (AKI) is regulated by transcriptional factors and microRNAs (miRs). However, modulation of miRs by transcriptional factors has not been characterized in AKI. Here, we found that urinary miR-16 was 100-fold higher in AKI patients. MiR-16 was dete...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Hsi-Hsien, Lan, Yi-Fan, Li, Hsiao-Fen, Cheng, Ching-Feng, Lai, Pei-Fang, Li, Wei-Hua, Lin, Heng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906401/
https://ncbi.nlm.nih.gov/pubmed/27297958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27945
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