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Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite Trypanosoma brucei
[Image: see text] The enzyme N-myristoyltransferase (NMT) catalyzes the essential fatty acylation of substrate proteins with myristic acid in eukaryotes and is a validated drug target in the parasite Trypanosoma brucei, the causative agent of African trypanosomiasis (sleeping sickness). N-Myristoyla...
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| Pubblicato in: | ACS Infect Dis |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2016
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906374/ https://ncbi.nlm.nih.gov/pubmed/27331140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00034 |
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