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Mechanisms of acetylcholine receptor loss in myasthenia gravis.

The fundamental abnormality affecting the neuromuscular junctions of myasthenic patients is a reduction of available AChRs, due to an autoimmune attack directed against the receptors. Antibodies to AChR are present in most patients, and there is evidence that they have a predominant pathogenic role...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Drachman, D B, Adams, R N, Stanley, E F, Pestronk, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1980
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC490627/
https://ncbi.nlm.nih.gov/pubmed/6249894
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