Regulation of acetylcholine receptor gene expression in human myasthenia gravis muscles. Evidences for a compensatory mechanism triggered by receptor loss.

Myasthenia gravis (MG) is a neuromuscular disorder mediated by antibodies directed against the acetylcholine receptor (nAChR) resulting in a functional nAChR loss. To analyze the molecular mechanisms involved at the muscular target site, we studied the expression of nAChR subunits in muscle biopsy s...

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Autors principals: Guyon, T, Wakkach, A, Poea, S, Mouly, V, Klingel-Schmitt, I, Levasseur, P, Beeson, D, Asher, O, Tzartos, S, Berrih-Aknin, S
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC509087/
https://ncbi.nlm.nih.gov/pubmed/9649579
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