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Understanding the Supersensitive Anti-Drug Antibody Assay: Unexpected High Anti-Drug Antibody Incidence and Its Clinical Relevance

Numbers of biotherapeutic products in development have increased over past decade. Despite providing significant benefits to patients with unmet needs, almost all protein-based biotherapeutics could induce unwanted immunogenicity, which result in a loss of efficacy and/or increase the risk of advers...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Song, Sam, Yang, Lili, Trepicchio, William L., Wyant, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906211/
https://ncbi.nlm.nih.gov/pubmed/27340678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3072586
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