Patch-Clamp Study of Hepatitis C p7 Channels Reveals Genotype-Specific Sensitivity to Inhibitors

Hepatitis C is a major worldwide disease and health hazard, affecting ∼3% of the world population. The p7 protein of hepatitis C virus (HCV) is an intracellular ion channel and pH regulator that is involved in the viral replication cycle. It is targeted by various classical ion channel blockers. Her...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biophys J
Egile Nagusiak: Breitinger, Ulrike, Farag, Noha S., Ali, Nourhan K.M., Breitinger, Hans-Georg A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2016
Gaiak:
Channels and Transporters
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906147/
https://ncbi.nlm.nih.gov/pubmed/27276260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.018
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