Combined Expression of IFN-γ, IL-17, and IL-4 mRNA by Recall PBMCs Moderately Discriminates Active Tuberculosis from Latent Mycobacterium tuberculosis Infection in Patients with Miscellaneous Inflammatory Underlying Conditions

New biomarkers are needed for discriminating active tuberculosis (TB) from latent TB infection (LTBI), especially in vulnerable groups representing the major diagnostic challenge. This pilot study was carried out to explore the diagnostic potential of selected genes, IFN-γ, IL-17, IL-4, and FoxP3, a...

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Udgivet i:Front Immunol
Main Authors: Savolainen, Laura E., Kantele, Anu, Knuuttila, Aija, Pusa, Liana, Karttunen, Riitta, Valleala, Heikki, Tuuminen, Tamara
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905973/
https://ncbi.nlm.nih.gov/pubmed/27379100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00239
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