Combined Expression of IFN-γ, IL-17, and IL-4 mRNA by Recall PBMCs Moderately Discriminates Active Tuberculosis from Latent Mycobacterium tuberculosis Infection in Patients with Miscellaneous Inflammatory Underlying Conditions

New biomarkers are needed for discriminating active tuberculosis (TB) from latent TB infection (LTBI), especially in vulnerable groups representing the major diagnostic challenge. This pilot study was carried out to explore the diagnostic potential of selected genes, IFN-γ, IL-17, IL-4, and FoxP3, a...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Savolainen, Laura E., Kantele, Anu, Knuuttila, Aija, Pusa, Liana, Karttunen, Riitta, Valleala, Heikki, Tuuminen, Tamara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905973/
https://ncbi.nlm.nih.gov/pubmed/27379100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00239
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