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Large Scale Chromosome Folding Is Stable against Local Changes in Chromatin Structure

Characterizing the link between small-scale chromatin structure and large-scale chromosome folding during interphase is a prerequisite for understanding transcription. Yet, this link remains poorly investigated. Here, we introduce a simple biophysical model where interphase chromosomes are described...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Florescu, Ana-Maria, Therizols, Pierre, Rosa, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905689/
https://ncbi.nlm.nih.gov/pubmed/27295501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004987
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