HIF-3α1 promotes colorectal tumor cell growth by activation of JAK-STAT3 signaling

Hypoxic environment is critical in colorectal cancer (CRC) development. Most studies have mainly focused on hypoxia-inducible factor (HIF)-1α and HIF-2α as the major hypoxic transcription factors in CRC development and progression. However, the role of HIF-3α in CRC is not clear. Here we found that...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Xue, Xiang, Jungles, Kylie, Onder, Gunseli, Samhoun, Jalal, Győrffy, Balázs, Hardiman, Karin M.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905494/
https://ncbi.nlm.nih.gov/pubmed/26871465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7272
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