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Bidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneity

Resolving the origin of intratumor heterogeneity has proven to be one of the central challenges in cancer research during recent years. Two theoretical models explaining the emergence of intratumor heterogeneity have come to dominate cancer biology literature: the clonal evolution model and the hier...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: van Neerven, Sanne M., Tieken, Mathijs, Vermeulen, Louis, Bijlsma, Maarten F.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905404/
https://ncbi.nlm.nih.gov/pubmed/27308617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1098791
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