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Alternative usage of initiation codons in mRNA encoding the cAMP-responsive-element modulator generates regulators with opposite functions.

The cAMP-responsive-element modulator (CREM) gene encodes both antagonists (CREM alpha/beta/gamma) and an activator (CREM tau) of cAMP-responsive transcription by alternative splicing. In adult mouse brain a predominant 21-kDa protein, not corresponding to any previously characterized transcript, is...

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Detalhes bibliográficos
Main Authors: Delmas, V, Laoide, B M, Masquilier, D, de Groot, R P, Foulkes, N S, Sassone-Corsi, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49054/
https://ncbi.nlm.nih.gov/pubmed/1584756
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