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CD44 regulates Wnt signaling at the level of LRP6

CD44 was recently identified as a positive feedback regulator of Wnt/β-catenin signaling. This regulation occurs at the level of low-density lipoprotein receptor-related protein 6 phosphorylation and membrane targeting. These findings broaden our understanding of the Wnt pathway activation process a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell Oncol
Main Authors: Orian-Rousseau, Véronique, Schmitt, Mark
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905321/
https://ncbi.nlm.nih.gov/pubmed/27308483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.995046
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