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Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer

We have recently explored the in vivo functional and oncologic relevance of Lon protease (LONP1), an enzyme involved in mitochondrial quality control. We found that LONP1 is an essential protein for life and that it also performs a critical function in tumorigenesis by regulating the bioenergetics o...

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Bibliografske podrobnosti
izdano v:Mol Cell Oncol
Main Authors: Quirós, Pedro M, Bárcena, Clea, López-Otín, Carlos
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905204/
https://ncbi.nlm.nih.gov/pubmed/27308364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.968505
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