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Moving ahead on harnessing synthetic lethality to fight cancer

We have recently developed a data-mining pipeline that comprehensively identifies cancer unique susceptibilities, following the concept of Synthetic Lethality (SL). The approach enables, for the first time, to identify and harness genome-scale SL-networks to accurately predict gene essentiality, dru...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Oncol
Autori principali: Jerby-Arnon, Livnat, Ruppin, Eytan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904895/
https://ncbi.nlm.nih.gov/pubmed/27308440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.977150
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