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Disrupting the dynamic equilibrium of ORAI channels determines the phenotype of malignant cells

We recently unraveled a finely tuned oncogenic mechanism in which genetic and tumor microenvironment alterations act together on a crucial calcium signaling pathway. This pathway involves an interconnected equilibrium of calcium channels functioning like a binary star system in which ORAI1 homomers...

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Détails bibliographiques
Publié dans:Mol Cell Oncol
Auteurs principaux: Vanden Abeele, Fabien, Dubois, Charlotte, Shuba, Yaroslav, Prevarskaya, Natalia
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904888/
https://ncbi.nlm.nih.gov/pubmed/27308432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.975631
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