Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells

The molecular nature of calcium (Ca(2+))-dependent mechanisms and the ion channels having a major role in the apoptosis of cancer cells remain a subject of debate. Here, we show that the recently identified Orai1 protein represents the major molecular component of endogenous store-operated Ca(2+) en...

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Detalhes bibliográficos
Main Authors: Flourakis, M, Lehen'kyi, V, Beck, B, Raphaël, M, Vandenberghe, M, Vanden Abeele, F, Roudbaraki, M, Lepage, G, Mauroy, B, Romanin, C, Shuba, Y, Skryma, R, Prevarskaya, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032347/
https://ncbi.nlm.nih.gov/pubmed/21364678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.52
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