Long-term in vivo polychlorinated biphenyl 126 exposure induces oxidative stress and alters proteomic profile on islets of Langerhans

It has been recently proposed that exposure to polychlorinated biphenyls (PCBs) is a risk factor to type 2 diabetes mellitus (DM2). We investigated this hypothesis using long-term in vivo PCB126 exposure to rats addressing metabolic, cellular and proteomic parameters. Male Wistar rats were exposed t...

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Pubblicato in:Sci Rep
Autori principali: Loiola, Rodrigo Azevedo, dos Anjos, Fabyana Maria, Shimada, Ana Lúcia, Cruz, Wesley Soares, Drewes, Carine Cristiane, Rodrigues, Stephen Fernandes, Cardozo, Karina Helena Morais, Carvalho, Valdemir Melechco, Pinto, Ernani, Farsky, Sandra Helena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904407/
https://ncbi.nlm.nih.gov/pubmed/27292372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27882
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