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Hollow Cone Electron Imaging for Single Particle 3D Reconstruction of Proteins

The main bottlenecks for high-resolution biological imaging in electron microscopy are radiation sensitivity and low contrast. The phase contrast at low spatial frequencies can be enhanced by using a large defocus but this strongly reduces the resolution. Recently, phase plates have been developed t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tsai, Chun-Ying, Chang, Yuan-Chih, Lobato, Ivan, Van Dyck, Dirk, Chen, Fu-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904375/
https://ncbi.nlm.nih.gov/pubmed/27292544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27701
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