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Drosophila Torsin Protein Regulates Motor Control and Stress Sensitivity and Forms a Complex with Fragile-X Mental Retardation Protein

We investigated unknown in vivo functions of Torsin by using Drosophila as a model. Downregulation of Drosophila Torsin (DTor) by DTor-specific inhibitory double-stranded RNA (RNAi) induced abnormal locomotor behavior and increased susceptibility to H(2)O(2). In addition, altered expression of DTor...

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Publicat a:Neural Plast
Autors principals: Nguyen, Phuong, Seo, Jong Bok, Ahn, Hyo-Min, Koh, Young Ho
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904285/
https://ncbi.nlm.nih.gov/pubmed/27313903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6762086
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