TRPV4 Regulates Breast Cancer Cell Extravasation, Stiffness and Actin Cortex

Metastasis is a significant health issue. The standard mode of care is combination of chemotherapy and targeted therapeutics but the 5-year survival rate remains low. New/better drug targets that can improve outcomes of patients with metastatic disease are needed. Metastasis is a complex process, wi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Wen Hsin, Choong, Lee Yee, Mon, Naing Naing, Lu, SsuYi, Lin, Qingsong, Pang, Brendan, Yan, Benedict, Krishna, Vedula Sri Ram, Singh, Himanshu, Tan, Tuan Zea, Thiery, Jean Paul, Lim, Chwee Teck, Tan, Patrick Boon Ooi, Johansson, Martin, Harteneck, Christian, Lim, Yoon Pin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904279/
https://ncbi.nlm.nih.gov/pubmed/27291497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27903
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