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Salinomycin Hydroxamic Acids: Synthesis, Structure, and Biological Activity of Polyether Ionophore Hybrids

[Image: see text] The polyether ionophore salinomycin has recently gained attention due to its exceptional ability to selectively reduce the proportion of cancer stem cells within a number of cancer cell lines. Efficient single step strategies for the preparation of hydroxamic acid hybrids of this c...

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Veröffentlicht in:ACS Med Chem Lett
Hauptverfasser: Borgström, Björn, Huang, Xiaoli, Chygorin, Eduard, Oredsson, Stina, Strand, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2016
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904257/
https://ncbi.nlm.nih.gov/pubmed/27326340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00079
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