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Breast cancer stem cell selectivity of synthetic nanomolar-active salinomycin analogs

BACKGROUND: Cancer stem cells (CSCs) have been invoked in resistance, recurrence and metastasis of cancer. Consequently, curative cancer treatments may be contingent on CSC selective approaches. Of particular interest in this respect is the ionophore salinomycin, a natural product shown to be 100-fo...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Huang, Xiaoli, Borgström, Björn, Kempengren, Sebastian, Persson, Lo, Hegardt, Cecilia, Strand, Daniel, Oredsson, Stina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765157/
https://ncbi.nlm.nih.gov/pubmed/26906175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2142-3
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