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Development of Potent and Selective S. aureus Sortase A Inhibitors Based on Peptide Macrocycles
[Image: see text] Sortases are transpeptidase enzymes that anchor surface proteins, including virulence factors, to the cell wall of Gram-positive bacteria, and they are potential targets for the development of anti-infective agents. While several large compound libraries were searched by high-throu...
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| Pubblicato in: | ACS Med Chem Lett |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2016
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4904248/ https://ncbi.nlm.nih.gov/pubmed/27326335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00045 |
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