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BWM*: A Novel, Provable, Ensemble-based Dynamic Programming Algorithm for Sparse Approximations of Computational Protein Design

Sparse energy functions that ignore long range interactions between residue pairs are frequently used by protein design algorithms to reduce computational cost. Current dynamic programming algorithms that fully exploit the optimal substructure produced by these energy functions only compute the GMEC...

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Publicat a:J Comput Biol
Autors principals: Jou, Jonathan D., Jain, Swati, Georgiev, Ivelin S., Donald, Bruce R.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904165/
https://ncbi.nlm.nih.gov/pubmed/26744898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2015.0194
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