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Diabetic Retinopathy and Transcriptional regulation of a Small Molecular Weight G-Protein, Rac1
In diabetic retinopathy, increased cytosolic reactive oxygen species, produced by NADPH oxidase (Nox), damage mitochondria, and this accelerates apoptosis of retinal capillary cells, resulting in the histopathology. Activation of Nox2 is mediated by a small molecular weight GTPase, Rac1, and retinal...
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| Publicado no: | Exp Eye Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4903942/ https://ncbi.nlm.nih.gov/pubmed/27109029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.04.014 |
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