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Efficient Biosynthesis of Fungal Polyketides Containing the Dioxabicyclo-octane Ring System
Aurovertins are fungal polyketides that exhibit potent inhibition of ATP synthase. Aurovertins contain a 2,6-dioxabicyclo[3.2.1]-octane ring that is proposed to be derived from a polyene precursor through regioselective oxidations and epoxide openings. In this study, we identified only four enzymes...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4903023/ https://ncbi.nlm.nih.gov/pubmed/26340065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b07816 |
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