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Perinatal HIV-1 transmission: Fc gamma receptor variability associates with maternal infectiousness and infant susceptibility

BACKGROUND: Accumulating data suggest that immune effector functions mediated through the Fc portion of HIV-1-specific immunoglobulin G (IgG) are a key component of HIV-1 protective immunity, affecting both disease progression and HIV-1 acquisition. Through studying Fc gamma receptor (FcγR) variants...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Lassaunière, Ria, Musekiwa, Alfred, Gray, Glenda E., Kuhn, Louise, Tiemessen, Caroline T.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902924/
https://ncbi.nlm.nih.gov/pubmed/27287460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0272-y
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