KIR-HLA and Maternal-Infant HIV-1 Transmission in Sub-Saharan Africa

Numerous studies have suggested a role for natural killer (NK) cells in attenuation of HIV-1 disease progression via recognition by killer-cell immunoglobulin-like receptors (KIRs) of specific HLA class I molecules. The role of KIR and HLA class I has not been addressed in the context of maternal-in...

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Main Authors: Paximadis, Maria, Minevich, Gregory, Winchester, Robert, Schramm, Diana B., Gray, Glenda E., Sherman, Gayle G., Coovadia, Ashraf H., Kuhn, Louise, Tiemessen, Caroline T.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035631/
https://ncbi.nlm.nih.gov/pubmed/21346814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016541
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