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Recapitulation of complex transport and action of drugs at tumor microenvironment using tumor-microenvironment-on-chip
Targeted delivery aims to selectively distribute drugs to targeted tumor tissue but not to healthy tissue. This can address many of clinical challenges by maximizing the efficacy but minimizing the toxicity of anti-cancer drugs. However, complex tumor microenvironment poses various barriers hinderin...
Gespeichert in:
Veröffentlicht in: | Cancer Lett |
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Hauptverfasser: | , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2015
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4902790/ https://ncbi.nlm.nih.gov/pubmed/26688098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.12.003 |
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