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Recapitulation of complex transport and action of drugs at tumor microenvironment using tumor-microenvironment-on-chip

Targeted delivery aims to selectively distribute drugs to targeted tumor tissue but not to healthy tissue. This can address many of clinical challenges by maximizing the efficacy but minimizing the toxicity of anti-cancer drugs. However, complex tumor microenvironment poses various barriers hinderin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Lett
Hauptverfasser: Han, Bumsoo, Qu, Chunjing, Park, Kinam, Konieczny, Stephen F., Korc, Murray
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902790/
https://ncbi.nlm.nih.gov/pubmed/26688098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.12.003
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