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Recapitulation of complex transport and action of drugs at tumor microenvironment using tumor-microenvironment-on-chip

Targeted delivery aims to selectively distribute drugs to targeted tumor tissue but not to healthy tissue. This can address many of clinical challenges by maximizing the efficacy but minimizing the toxicity of anti-cancer drugs. However, complex tumor microenvironment poses various barriers hinderin...

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Foilsithe in:Cancer Lett
Main Authors: Han, Bumsoo, Qu, Chunjing, Park, Kinam, Konieczny, Stephen F., Korc, Murray
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902790/
https://ncbi.nlm.nih.gov/pubmed/26688098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.12.003
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