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Recapitulation of complex transport and action of drugs at tumor microenvironment using tumor-microenvironment-on-chip

Targeted delivery aims to selectively distribute drugs to targeted tumor tissue but not to healthy tissue. This can address many of clinical challenges by maximizing the efficacy but minimizing the toxicity of anti-cancer drugs. However, complex tumor microenvironment poses various barriers hinderin...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Han, Bumsoo, Qu, Chunjing, Park, Kinam, Konieczny, Stephen F., Korc, Murray
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902790/
https://ncbi.nlm.nih.gov/pubmed/26688098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.12.003
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