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Potential therapeutic approaches for Angelman syndrome
INTRODUCTION: Angelman syndrome (AS) is a neurodevelopmental disorder caused by deficiency of maternally inherited UBE3A, an ubiquitin E3 ligase. Despite recent progress in understanding the mechanism underlying UBE3A imprinting, there is no effective treatment. Further investigation of the roles pl...
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| Publicado no: | Expert Opin Ther Targets |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4902328/ https://ncbi.nlm.nih.gov/pubmed/26558806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2016.1115837 |
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