Hexavalent Chromium (Cr(VI)) Down-Regulates Acetylation of Histone H4 at Lysine 16 through Induction of Stressor Protein Nupr1

The environmental and occupational carcinogen Hexavalent Chromium (Cr(VI)) has been shown to cause lung cancer in humans when inhaled. In spite of a considerable research effort, the mechanisms of Cr(VI)-induced carcinogenesis remain largely unknown. Nupr1 (nuclear protein 1) is a small, highly basi...

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Vydáno v:PLoS One
Hlavní autoři: Chen, Danqi, Kluz, Thomas, Fang, Lei, Zhang, Xiaoru, Sun, Hong, Jin, Chunyuan, Costa, Max
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902237/
https://ncbi.nlm.nih.gov/pubmed/27285315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157317
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